Antibacterial Activity, Phytochemical and Proximate Analysis of Moringa Oleifera Seeds Against Clinical Isolates

Abstract

This study was carried out to determine the antibacterial activity, phytochemical
and proximate analysis of Moringa oleifera seeds extracts against some clinical
isolates. The antibacterial activity for Aqueous and Ethanol extracts was
determined using the agar diffusion method. The Phytochemical Screening of
the seed was carried out using Qualitative Analysis (QA) and proximate analysis
was carried out according to AOAC methods. The aqueous seed extract
showed varying degrees of antimicrobial activity over that of ethanol extract on
the microorganisms tested. Two species (Staphylococcus aureus and
Salmonella typhi) presented the lowest MIC of 31.25 and 125mg/ml compared
to MBC of 250mg/ml respectively. The phytochemical revealed the presence of
Flavonoids, Tannins, Alkaloid, and Saponins. The Proximate Analysis revealed
high concentration of Crude lipid (35.58 ± 0.42%) and lowest concentration of
Moisture content (2.03 ± 0.01%). This study shows that moringa oleifera seeds
can be as effective as synthetic medicine to combat pathogenic microorganisms
if properly utilized.