Analysis of sildenafil citrate in herbal aphrodisiac preparations marketed in Sokoto metropolis and its public health implications
Keywords:Sildenafil citrate, herbal-aphrodisiac, adulteration,, undeclared,, TLC.
Aphrodisiacs are among the most widely marketed and consumed herbal products in North-Western Nigeria. There are speculations that these products are being adulterated with orthodox medicines in order to boost their effects and sales. The objective of current research was to analyse the presence of adulterated sildenafil citrate in some herbal aphrodisiacs commonly sold and consumed in Sokoto metropolis. Ten different liquid herbal aphrodisiac preparations marketed in Sokoto metropolis were collected from different areas of the city. Each of the preparation was analysed for adulteration with sildenafil citrate using thin layer chromatography and UV spectroscopy. Five of the preparations were found to contain sildenafil citrate in the range of 34 – 291 mg per daily dose. The findings from this study indicate that some of the herbal aphrodisiac preparations marketed in Sokoto metropolis are being adulterated with substantial amount of undeclared sildenafil citrate, a practice that poses serious public health hazard to its consumers. Consequences of which ranges from nausea, dyspepsia, pain, dizziness, abnormal vision, and headache and potentially heart attack especially among adults with underlying chronic diseases such as hypertension among others.